author={Fleming Carswell and Stephen J. Thompson},
  journal={The Lancet},
House dust mite allergy and atopic eczema:a case report
The results suggest that large amounts of house dust mite antigen may be scratched into the skin during clinical exacerbations of the eczema, this in turn aggravating the state of the skin because of hypersensitivity to the mite.
Severity of atopic dermatitis in relation to food and inhalant allergy in adults and adolescents
It turns out that the higher time to reaction, the higher the severity of AD, and the significant relation was also found between the severity and IgE-mediated food allergy.
Temporal association between Der pI exposure, immediate hypersensitivity and clinical severity of eczema
It is concluded that the observed changes in clinical severity were unlikely to be due to immediate hypersensitivity responses to natural variations in Der pI concentrations in the personal environments of these subjects.
Atopic dermatitis and house dust mites
The higher exposure to house dust mites corresponded to a relative risk of 4.6 and a clear dose‐response relationship between exposure and disease could be demonstrated.
House‐dust mite content in mattresses in relation to residential characteristics and symptoms in atopic and nonatopic children living in northern Norway
Poor ventilation, increased humidity, and water leak(s) were associated with the presence of domestic mites in mattresses, and it should be possible to avoid HDM exposure and allergy in this region.
Exposure to house dust mites in homes of people with atopic dermatitis
  • M. Colloff
  • Biology
    The British journal of dermatology
  • 1992
It is hypothesized that the association between high densities of mites and AD is related to differences in lipid composition of the shed squames on which the mites feed: those of people with AD may be of greater nutritional value than those of non‐atopics, thus enhancing mite population growth.
Immunoblot multi‐allergen inhibition studies of allergenic cross‐reactivity of the dust mites Lepidoglyphus destructor and Dermatophagoides pteronyssinus
The allergenic similarity of the pyroglyphid mite D. pteronyssinus and the glycyphagid mite L. destructor was investigated with a new immunoblotting inhibition technique allowing simultaneous
Latex Allergy in Children with No Known Risk Factors for Sensitization
It is proposed that children from an atopic background with eczema or other inflammatory conditions are at increased risk of latex allergy after prolonged exposure to latex.


Role of house-dust mites in childhood asthma
In vitro studies of specific IgE levels were found to bear a close relation to nasal provocation tests and probably have an important place in the identification of offending allergens in the paediatric patient.
The role of dust mite allergens in atopic dermatitis
It now seems likely that allergens which cause immediate reactions in the skin can give rise to chronic changes in the lungs.
Exercise-induced bronchocontriction, skin sensitivity, and serum IgE in children with eczema.
It is suggested that in a proportion of chilren with eczema there is little evidence of reaginic allergy, other than Eczema and skin sensitivity, and total IgE fell within the normal range.
Eczematous reactions in atopic patients caused by epicutaneous testing with inhalant allergens
Biopsies of the positive test sites revealed an eczematous reaction with epidermal spongiosis and microvesiculation in patients with atopic eczema, and no delayed type test reactions to either allergen were seen in the controls.
Mite faeces are a major source of house dust allergens
Measurements from a radioimmunoassay show that more than 95% of the allergen accumulating in mite cultures is associated with faecal particles.
Identification of Allergens in Dermatophagoides pteronyssinus Mite Body Extract by Crossed Radioimmunoelectrophoresis with Two Different Rabbit Antibody Pools
An extract of purified Dermatophagoides pteronyssinus mite bodies was investigated by crossed radioimmunoelectrophoresis (CRIE), using sera from 29 mite‐allergic patterns, finding specific response patterns in the studied set of sera to several of the represented antigens.
T cell responses to the major allergen from the house dust mite Dermatophagoides pteronyssinus, Antigen P1: comparison of patients with asthma, atopic dermatitis, and perennial rhinitis.
The results indicate that most patients showing immediate hypersensitivity to D. pteronyssinus have circulating T cells sensitized to Antigen P1, which may also play a role in the pathogenesis of allergic lesions and in the delayed or chronic symptoms of these allergic diseases.
Predisposing factors and the development of reaginic allergy in infancy
The study of newborn infants of parents with reaginic allergy suggests that sensitization in the new‐born period is important in the subsequent development of disease.
Cutaneous basophil hypersensitivity to inhalant allergens in atopic dermatitis patients: elicitation of delayed responses containing basophils following local transfer of immune serum but not IgE antibody.
The results suggest that while the allergen-induced patch test response may involve IgE antibodies, as well as the cells normally involved in delayed responses, another serum activity is also involved.
Measurement of IgG, IgA and IgE antibodies to Dermatophagoides pteronyssinus by antigen-binding assay, using a partially purified fraction of mite extract (F4P1).
An extract of Dermatophagoides pteronyssinus culture has been fractionated by chromatography on Sephadex G-100 and Pevikon block electrophoresis to obtain a partially purified allergen (F4P1), which was radio-labelled with 125I and used in an antigen-binding radioimmunoassay to measure IgG, IgA and IgE antibody to D. pterONYssinus.