DOC and GCA blocks the reduction of hypothalamic CRF containing neurons due to repetitive stress


Stress stimulates multiple adaptive hormonal responses including the secretion of corticotrophin releasing factor (CRF), adrenocorticotrophic hormone (ACTH), β-endorphin and corticosteroids. There are two major systems involved in stress responses, the CRF system or the hypothalamo pituitary adrenal axis (HPA) system and the locus caeruleus or sympathetic… (More)


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