DNase I homologous residues in CdtB are critical for cytolethal distending toxin-mediated cell cycle arrest.

@article{Elwell2000DNaseIH,
  title={DNase I homologous residues in CdtB are critical for cytolethal distending toxin-mediated cell cycle arrest.},
  author={C A Elwell and Lawrence A. Dreyfus},
  journal={Molecular microbiology},
  year={2000},
  volume={37 4},
  pages={952-63}
}
Cytolethal distending toxins (CDTs) block cell division by arresting the eukaryotic cell cycle at G2/M. Although previously not recognized in standard BLAST searches, a position-specific iterated (PSI) BLAST search of the protein data bank using CDT polypeptides as query sequences indicated that CdtB bears significant position-specific homology to type I… CONTINUE READING