DNAM-1 controls NK cell activation via an ITT-like motif

Abstract

DNAM-1 (CD226) is an activating receptor expressed on natural killer (NK) cells, CD8(+) T cells, and other immune cells. Upon recognition of its ligands, CD155 and CD112, DNAM-1 promotes NK cell-mediated elimination of transformed and virus-infected cells. It also has a key role in expansion and maintenance of virus-specific memory NK cells. Herein, the… (More)
DOI: 10.1084/jem.20150792

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@inproceedings{Zhang2015DNAM1CN, title={DNAM-1 controls NK cell activation via an ITT-like motif}, author={Zhanguang Zhang and Ning Wu and Yan Lu and Dominique Davidson and Marco Colonna and Andr{\'e} Veillette}, booktitle={The Journal of experimental medicine}, year={2015} }