DNA vaccines: immunology, application, and optimization*.

  title={DNA vaccines: immunology, application, and optimization*.},
  author={Sanjay Gurunathan and Dennis M Klinman and Robert A. Seder},
  journal={Annual review of immunology},
The development and widespread use of vaccines against infectious agents have been a great triumph of medical science. One reason for the success of currently available vaccines is that they are capable of inducing long-lived antibody responses, which are the principal agents of immune protection against most viruses and bacteria. Despite these successes, vaccination against intracellular organisms that require cell-mediated immunity, such as the agents of tuberculosis, malaria, leishmaniasis… CONTINUE READING
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