DNA vaccine protects ornamental koi (Cyprinus carpio koi) against North American spring viremia of carp virus.

@article{Emmenegger2008DNAVP,
  title={DNA vaccine protects ornamental koi (Cyprinus carpio koi) against North American spring viremia of carp virus.},
  author={E J Emmenegger and Gael Kurath},
  journal={Vaccine},
  year={2008},
  volume={26 50},
  pages={6415-21}
}
The emergence of spring viremia of carp virus (SVCV) in the United States constitutes a potentially serious alien pathogen threat to susceptible fish stocks in North America. A DNA vaccine with an SVCV glycoprotein (G) gene from a North American isolate was constructed. In order to test the vaccine a challenge model utilizing a specific pathogen-free domestic koi stock and a cold water stress treatment was also developed. We have conducted four trial studies demonstrating that the pSGnc DNA… CONTINUE READING

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