DNA uptake during bacterial transformation

  title={DNA uptake during bacterial transformation},
  author={In{\^e}s Chen and David Dubnau},
  journal={Nature Reviews Microbiology},
Naturally competent bacteria are able to take up exogenous DNA and undergo genetic transformation. The transport of DNA from the extracellular milieu into the cytoplasm is a complex process, and requires proteins that are related to those involved in the assembly of type IV pili and type II secretion systems, as well as a DNA translocase complex at the cytoplasmic membrane. Here, we will review the current knowledge of DNA transport during transformation. 
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