DNA typing of HLA class II genes; DRB1*0803 increases the susceptibility of Japanese to primary biliary cirrhosis.

@article{Onishi1994DNATO,
  title={DNA typing of HLA class II genes; DRB1*0803 increases the susceptibility of Japanese to primary biliary cirrhosis.},
  author={Saburo Onishi and Tateo Sakamaki and Takashi Maeda and Shin-ichi Iwamura and Aiko Tomita and Toshiji Saibara and Yoshiya Yamamoto},
  journal={Journal of hepatology},
  year={1994},
  volume={21 6},
  pages={1053-60}
}
The association between human leukocyte antigens and primary biliary cirrhosis is controversial, but major histocompatibility complex class II antigen DR8 was recently reported to be associated with increased susceptibility for primary biliary cirrhosis in some Caucasians and Japanese. Accordingly, we performed DNA typing of HLA class II genes in Japanese patients with primary biliary cirrhosis. The genotypes of HLA DRB1, DRB3-5, DQA and DQB were determined by polymerase chain reaction and… CONTINUE READING

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