DNA tetraplex formation studied with fluorescence resonance energy transfer.

@article{Simonsson1999DNATF,
  title={DNA tetraplex formation studied with fluorescence resonance energy transfer.},
  author={Tomas Simonsson and Robert Sj{\"o}back},
  journal={The Journal of biological chemistry},
  year={1999},
  volume={274 24},
  pages={17379-83}
}
It is emerging that DNA tetraplexes are pivotal for many major cellular processes, and techniques that assess their structure and nature to the point are under development. Here we show how the structural conversion of largely unstructured single-stranded DNA molecules into compact intrastrand DNA tetraplexes can be monitored by fluorescence resonance energy transfer. We recently reported that intrastrand tetraplex formation takes place in a nuclease hypersensitive element upstream of the human… CONTINUE READING

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