DNA testing for fragile X syndrome in schools for learning difficulties.

@article{Slaney1995DNATF,
  title={DNA testing for fragile X syndrome in schools for learning difficulties.},
  author={Sarah F. Slaney and Andrew O M Wilkie and Mark Hirst and R R Charlton and Mark Mckinley and Joel Pointon and Z{\'o}e Christodoulou and Susan Mary Huson and K. E. Davies},
  journal={Archives of disease in childhood},
  year={1995},
  volume={72 1},
  pages={33-7}
}
Fragile X syndrome is the most common inherited cause of mental retardation. Early diagnosis is important not only for appropriate management of individuals but also to identify carriers who are unaware of their high risk of having an affected child. The disorder is associated with a cytogenetically visible fragile site (FRAXA) at Xq27.3, caused by amplification of a (CGG)n repeat sequence within the gene at this locus designated FMR1. Clinical and molecular studies have been undertaken to… CONTINUE READING