DNA surface coating of calixarene-based nanoparticles: a sequence-dependent binding mechanism.

Abstract

An amphiphilic calix[4]arene derivative bearing four guanidino moieties at the upper rim and four dodecyl chains at the lower rim was shown to form stable solid lipid nanoparticles (SLNs) in water. The study of the interactions of these cationic SLNs with DNA revealed a sequence-dependent groove binding mechanism. 
DOI: 10.1039/c2cc36859e

Topics

1 Figure or Table

Cite this paper

@article{Rullaud2012DNASC, title={DNA surface coating of calixarene-based nanoparticles: a sequence-dependent binding mechanism.}, author={Vanessa Rullaud and Michael Siragusa and Alessandro Cumbo and Daniel Gygax and Patrick Shahgaldian}, journal={Chemical communications}, year={2012}, volume={48 100}, pages={12186-8} }