DNA structure dependent checkpoints as regulators of DNA repair.

Abstract

Checkpoint proteins were initially identified because their loss of function resulted in defects in cell cycle arrest in response to genotoxic treatments. Initially, the analysis of checkpoint pathways concentrated on their function as signal transducers and how the checkpoint signals were communicated to the core cell cycle machinery and transcriptional… (More)

Topics

Cite this paper

@article{Carr2002DNASD, title={DNA structure dependent checkpoints as regulators of DNA repair.}, author={Antony M. Carr}, journal={DNA repair}, year={2002}, volume={1 12}, pages={983-94} }