DNA structural variations in the E. coli tyrT promoter.

  title={DNA structural variations in the E. coli tyrT promoter.},
  author={Horace R. Drew and Andrew Travers},
  volume={37 2},
X-ray studies have established that the structure of a right-handed, Watson-Crick double helix can change from place to place along its length as a function of base sequence. The base pairs transmit deformations out to the phosphate backbone, where they can then be recognized by proteins and other DNA-binding reagents. Here we have examined at single-bond resolution the interactions of three commonly used nucleases (DNAase I, DNAase II, and copper-phenanthroline) with a DNA of natural origin… CONTINUE READING