DNA strand breaks in human nasal respiratory epithelium are induced upon exposure to urban pollution.

@article{CalderonGarciduenas1996DNASB,
  title={DNA strand breaks in human nasal respiratory epithelium are induced upon exposure to urban pollution.},
  author={Lilian C. Calderon-Garciduenas and N Osnaya-Brizuela and L Ramirez-Martinez and Anna Villarreal-Calder{\'o}n},
  journal={Environmental Health Perspectives},
  year={1996},
  volume={104},
  pages={160 - 168}
}
All organisms have the ability to respond and adapt to a myriad of environmental insults. The human respiratory epithelium, when exposed to oxidant gases in photochemical smog, is at risk of DNA damage and requires efficient cellular adaptative responses to resist the environmentally induced cell damage. Ozone and its reaction products induce in vitro and in vivo DNA single strand breaks (SSBs) in respiratory epithelial cells and alveolar macrophages. To determine if exposure to a polluted… CONTINUE READING
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