DNA slows dissociation of progesterone receptor–steroid ligand complexes

@article{Pokrovskaya2003DNASD,
  title={DNA slows dissociation of progesterone receptor–steroid ligand complexes},
  author={E. Pokrovskaya and I. S. Levina and A. V. Kamernitsky and V. P. Shevchenko and A. N. Smirnov},
  journal={Steroids},
  year={2003},
  volume={68},
  pages={351-359}
}
Steroid ligands are known to affect the interactions of their respective receptors with DNA. In the present study, the possibility of DNA interference in progesterone receptor-ligand interactions was investigated. An oligonucleotide containing a hormone response element (HRE) was shown to decrease the dissociation rate of complexes of [3H]progesterone or [3H]16alpha,17alpha-cycloalkanoprogesterones with PRs from rabbit and rat uterine cytosol. The extent to which the oligonucleotide affected… Expand
Modulation of Folate Receptor-alpha by Glucocorticoid Receptor and Progesterone Receptor

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