DNA sequencing: bench to bedside and beyond†

@inproceedings{Hutchison2007DNASB,
  title={DNA sequencing: bench to bedside and beyond†},
  author={Clyde A. Hutchison},
  booktitle={Nucleic acids research},
  year={2007}
}
Fifteen years elapsed between the discovery of the double helix (1953) and the first DNA sequencing (1968). Modern DNA sequencing began in 1977, with development of the chemical method of Maxam and Gilbert and the dideoxy method of Sanger, Nicklen and Coulson, and with the first complete DNA sequence (phage X174), which demonstrated that sequence could give profound insights into genetic organization. Incremental improvements allowed sequencing of molecules >200 kb (human cytomegalovirus… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.
74 Citations
102 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 74 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 102 references

A Life Decoded

  • J. C. Venter
  • 2007
1 Excerpt

Similar Papers

Loading similar papers…