DNA sequence-directed organization of chromatin: structure-based computational analysis of nucleosome-binding sequences.

Abstract

The folding of DNA on the nucleosome core particle governs many fundamental issues in eukaryotic molecular biology. In this study, an updated set of sequence-dependent empirical "energy" functions, derived from the structures of other protein-bound DNA molecules, is used to investigate the extent to which the architecture of nucleosomal DNA is dictated by… (More)
DOI: 10.1016/j.bpj.2008.11.040

Cite this paper

@article{Balasubramanian2009DNASO, title={DNA sequence-directed organization of chromatin: structure-based computational analysis of nucleosome-binding sequences.}, author={Sreekala Balasubramanian and Fei Xu and Wilma K. Olson}, journal={Biophysical journal}, year={2009}, volume={96 6}, pages={2245-60} }