DNA replication at the single-molecule level.

@article{Stratmann2014DNARA,
  title={DNA replication at the single-molecule level.},
  author={Sarah A Stratmann and Antoine M. van Oijen},
  journal={Chemical Society reviews},
  year={2014},
  volume={43 4},
  pages={
          1201-20
        }
}
A cell can be thought of as a highly sophisticated micro factory: in a pool of billions of molecules - metabolites, structural proteins, enzymes, oligonucleotides - multi-subunit complexes assemble to perform a large number of basic cellular tasks, such as DNA replication, RNA/protein synthesis or intracellular transport. By purifying single components and using them to reconstitute molecular processes in a test tube, researchers have gathered crucial knowledge about mechanistic, dynamic and… 
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