DNA repair is more important than catalase for Salmonella virulence in mice.

@article{Buchmeier1995DNARI,
  title={DNA repair is more important than catalase for Salmonella virulence in mice.},
  author={Nancy Buchmeier and Stephen James Libby and Yan Xu and Peter C Loewen and Jacek Switala and Donald G. Guiney and Ferric C Fang},
  journal={The Journal of clinical investigation},
  year={1995},
  volume={95 3},
  pages={1047-53}
}
Pathogenic microorganisms possess antioxidant defense mechanisms for protection from reactive oxygen metabolites such as hydrogen peroxide (H2O2), which are generated during the respiratory burst of phagocytic cells. These defense mechanisms include enzymes such as catalase, which detoxify reactive oxygen species, and DNA repair systems which repair damage resulting from oxidative stress. To determine the relative importance of these two potentially protective defense mechanisms against… CONTINUE READING
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