DNA repair genes in endometriosis.

  title={DNA repair genes in endometriosis.},
  author={Rukset Attar and Canan Cacina and S. Numan Sozen and Erkut Attar and Bedia Ağaçhan},
  journal={Genetics and molecular research : GMR},
  volume={9 2},
Several polymorphisms in the DNA repair gene are thought to have significant effects on cancer risk. We investigated the association of polymorphisms in the DNA repair genes XRCC1 Arg399Gln, XRCC3 Thr241Met, XPD Lys751Gln, XPG Asp1104His, APE1 Asp148Glu, and HOGG1 Ser326Cys with endometriosis risk. Genotypes were determined by PCR-RFLP assays in 52 patients with endometriosis and 101 age-matched healthy controls. Although there were no significant (P > 0.05) differences in the frequencies of… CONTINUE READING