DNA repair gene XRCC1 polymorphisms, smoking, and esophageal cancer risk.

@article{Yu2004DNARG,
  title={DNA repair gene XRCC1 polymorphisms, smoking, and esophageal cancer risk.},
  author={Hong-ping Yu and Xiao-Yong Zhang and Xiao-Li Wang and Lu-yuan Shi and Yuan-yuan Li and Fang Li and Su Ya-Qiong and You-jie Wang and Bin Lu and Xi Sun and Wen-hong Lu and Shun-qing Xu},
  journal={Cancer detection and prevention},
  year={2004},
  volume={28 3},
  pages={
          194-9
        }
}
To investigate the effect of X-ray repair cross complementing 1 (XRCC1) genetic polymorphisms on esophageal cancer risk, we determined XRCC1 polymorphisms at codon 194 (Arg --> Trp) and codon 399 (Arg --> Gln) in 135 patients with esophageal squamous cell carcinoma (ESCC) and 152 normal controls from hospitals. Although polymorphism at codon 194 was not associated with risk for ESCC, we found that the frequency of XRCC1 399 Gln/Gln genotype in ESCC patients (14.1%) was significantly higher than… CONTINUE READING
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Association between the c.910A>G genetic variant of the XRCC1 gene and susceptibility to esophageal cancer in the Chinese Han population

  • Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
  • 2013
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