DNA repair gene XRCC1 and XRCC4 variations and risk of endometriosis: an association study.

@article{Saliminejad2015DNARG,
  title={DNA repair gene XRCC1 and XRCC4 variations and risk of endometriosis: an association study.},
  author={Kioomars Saliminejad and Mitra Saket and Koorosh Kamali and Toktam Memariani and Hamid Reza Khorram Khorshid},
  journal={Gynecologic and obstetric investigation},
  year={2015},
  volume={80 2},
  pages={85-8}
}
BACKGROUND Endometriosis is a polygenic and multifactorial disease. DNA damage plays a major role in mutagenesis, carcinogenesis and aging and is usually repaired by the action of several DNA repair enzymes. We investigated the association of the common variations of the DNA repair genes XRCC1 and XRCC4 with susceptibility to endometriosis in an Iranian population. METHODS In total, 160 patients with endometriosis (stages I-IV) and 174 healthy women were included in this case-control study… CONTINUE READING
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