DNA repair gene XPD and susceptibility to arsenic-induced hyperkeratosis.

@article{Ahsan2003DNARG,
  title={DNA repair gene XPD and susceptibility to arsenic-induced hyperkeratosis.},
  author={Habibul Ahsan and Yu Chen and Qiao Wang and Vesna N Slavkovich and Joseph H. Graziano and Regina M. Santella},
  journal={Toxicology letters},
  year={2003},
  volume={143 2},
  pages={123-31}
}
Chronic exposure to inorganic arsenic is known to cause non-melanocytic skin and internal cancers in humans. An estimated 50-70 million people in Bangladesh have been chronically exposed to arsenic from drinking water and are at risk of skin and other cancers. We undertook the first study to examine whether genetic susceptibility, as determined by the codon 751 SNP (A-->C) of the DNA repair gene XPD, influences the risk of arsenic-induced hyperkeratotic skin lesions, precursors of skin cancer… CONTINUE READING

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