DNA repair capacity after gamma-irradiation and expression profiles of DNA repair genes in resting and proliferating human peripheral blood lymphocytes.

@article{Mayer2002DNARC,
  title={DNA repair capacity after gamma-irradiation and expression profiles of DNA repair genes in resting and proliferating human peripheral blood lymphocytes.},
  author={Claudia Mayer and Odilia Popanda and Otto Zelezny and Marie-Charlotte von Brevern and Alfred Bach and Helmut Bartsch and Peter Schmezer},
  journal={DNA repair},
  year={2002},
  volume={1 3},
  pages={237-50}
}
DNA repair plays an important role in maintaining genomic integrity, and deficiencies in repair function are known to promote cancer development. Several studies have used the individual capacity to repair DNA damage in peripheral blood lymphocytes (PBLs) as a cancer risk marker. As the cell's ability to remove DNA damage may be correlated with proliferative activity, it is an important question whether quiescent or dividing cells should be used in such studies. The aim of our study was to… CONTINUE READING
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