DNA rearrangement mediated by inverted repeats.

  title={DNA rearrangement mediated by inverted repeats.},
  author={X Bi and L. F. Liu},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={93 2},
  • X. Bi, L. Liu
  • Published 1996
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
Inverted repeats of DNA are widespread in the genomes of eukaryotes and prokaryotes and can mediate genome rearrangement. We studied rearrangement mediated by plasmid-borne inverted repeats in Escherichia coli. We show that inverted repeats can mediate an efficient and recA-independent recombination event. Surprisingly, the product of this recombination is not that of simple inversion between the inverted repeats, but almost exclusively an unusual head-to-head dimer with complex DNA… Expand
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In contrast with earlier studies on the lambda and Escherichia coli genomes, recombination between inverted repeats on plasmids is highly efficient and shown to be recA-independent. In addition, theExpand
Factors affecting inverted repeat stimulation of recombination and deletion in Saccharomyces cerevisiae.
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This chapter catalogs several types of misalignment-mediated genetic changes in bacteria, with an emphasis on the mechanisms by which they occur. Expand
recA-independent DNA recombination between repetitive sequences: mechanisms and implications.
  • X. Bi, L. Liu
  • Biology, Medicine
  • Progress in nucleic acid research and molecular biology
  • 1996
Publisher Summary This chapter discusses the distinct features of recA -independent recombination among repetitive sequences in bacteria, with special emphasis on replicational models and theirExpand
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