DNA-protein cross-links and sister chromatid exchange frequencies in lymphocytes and hydroxyethyl mercapturic acid in urine of ethylene oxide-exposed hospital workers.

@article{Popp1994DNAproteinCA,
  title={DNA-protein cross-links and sister chromatid exchange frequencies in lymphocytes and hydroxyethyl mercapturic acid in urine of ethylene oxide-exposed hospital workers.},
  author={Walter Popp and Carola Vahrenholz and H Przygoda and Andreas Brauksiepe and S Goch and G{\"u}nter M{\"u}ller and Connie Schell and Klaus Norpoth},
  journal={International archives of occupational and environmental health},
  year={1994},
  volume={66 5},
  pages={325-32}
}
The lymphocytes of 25 hospital workers exposed to ethylene oxide and of a standardized control group were investigated for DNA damage (measured by alkaline filter elution) and sister chromatid exchange (SCE) frequencies. Additionally, the excretion of hydroxyethyl mercapturic acid (HEMA) in the 24-h urine of ten workers and ten control persons was determined. The peak levels of ethylene oxide in air during the first 8 min after opening of the sterilization unit were measured. Peak levels of… CONTINUE READING