DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae.

@article{Broomfield2001DNAPR,
  title={DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae.},
  author={Stacey Broomfield and Todd Hryciw and Wei Xiao},
  journal={Mutation research},
  year={2001},
  volume={486 3},
  pages={167-84}
}
DNA postreplication repair (PRR) is defined as an activity to convert DNA damage-induced single-stranded gaps into large molecular weight DNA without actually removing the replication-blocking lesions. In bacteria such as Escherichia coli, this activity requires RecA and the RecA-mediated SOS response and is accomplished by recombination and mutagenic translesion DNA synthesis. Eukaryotic cells appear to share similar DNA damage tolerance pathways; however, some enzymes required for PRR in… CONTINUE READING
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