DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae.

  title={DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae.},
  author={Stacey Broomfield and Todd Hryciw and Wei Xiao},
  journal={Mutation research},
  volume={486 3},
DNA postreplication repair (PRR) is defined as an activity to convert DNA damage-induced single-stranded gaps into large molecular weight DNA without actually removing the replication-blocking lesions. In bacteria such as Escherichia coli, this activity requires RecA and the RecA-mediated SOS response and is accomplished by recombination and mutagenic translesion DNA synthesis. Eukaryotic cells appear to share similar DNA damage tolerance pathways; however, some enzymes required for PRR in… CONTINUE READING
Highly Influential
This paper has highly influenced 11 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS