DNA polymorphisms at the lipoprotein lipase gene are associated with macroangiopathy in type 2 (non-insulin-dependent) diabetes mellitus.

@article{Ukkola1995DNAPA,
  title={DNA polymorphisms at the lipoprotein lipase gene are associated with macroangiopathy in type 2 (non-insulin-dependent) diabetes mellitus.},
  author={Olavi H Ukkola and Markku J. Savolainen and Pasi I. Salmela and K J von Dickhoff and Yrj{\"o} Antero Kes{\"a}niemi},
  journal={Atherosclerosis},
  year={1995},
  volume={115 1},
  pages={99-105}
}
We studied the effect of variation at the lipoprotein lipase (LPL) gene locus on the susceptibility of individuals with Type 2 diabetes mellitus to atherosclerotic vascular disease in a population of 126 male and 114 female patients. The prevalence of any evidence of coronary heart disease (CHD) (presence of ischaemic ECG changes or definite myocardial infarction) was low in the patients who were homozygous for the presence of the PvuII restriction site (genotype 2-2) (40.9%) compared with… CONTINUE READING