DNA polymerases in prokaryotes and eukaryotes: Mode of action and biological implications

@article{Hbscher1983DNAPI,
  title={DNA polymerases in prokaryotes and eukaryotes: Mode of action and biological implications},
  author={Ulrich H{\"u}bscher},
  journal={Experientia},
  year={1983},
  volume={39},
  pages={1-25}
}
DNA transactions such as replication, repair and recombination require the concerted action of many proteins either alone or in a complex 1. Nevertheless, in all these processes one protein, the DNA polymerase, plays a central role. Its function is to ensure the accurate incorporation of the 4 deoxyribonucleoside triphosphates (dATP, dCTP, dGTP and dTTP) on a mother template according to the Watson-Crick base pairing rules (A to T and G to C). Since the discovery of the first DNA polymerase… CONTINUE READING

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