DNA polymerases as engines for biotechnology.

@article{Hamilton2001DNAPA,
  title={DNA polymerases as engines for biotechnology.},
  author={Sarah C. Hamilton and Joseph W Farchaus and Michael Christopher Davis},
  journal={BioTechniques},
  year={2001},
  volume={31 2},
  pages={
          370-6, 378-80, 382-3
        }
}
This review examines the DNA polymerases, a class of enzymes that has been an essential tool for molecular biology research. Several families of DNA polymerases have been defined based on amino acid sequence comparisons, and new enzymes are continually being discovered, driving the expansion of the current classifications. Structural similarities among the enzymes are examined, as well as the functions of the various subunits and enzyme domains. The natural variety of polymerase activities has… CONTINUE READING
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