DNA polymerase template switching at specific sites on the phi29 genome causes the in vivo accumulation of subgenomic phi29 DNA molecules.

@article{Murthy1998DNAPT,
  title={DNA polymerase template switching at specific sites on the phi29 genome causes the in vivo accumulation of subgenomic phi29 DNA molecules.},
  author={Vasudeva Murthy and Wilfried J J Meijer and Luis Blanco and M. Salas},
  journal={Molecular microbiology},
  year={1998},
  volume={29 3},
  pages={787-98}
}
The accumulation of subgenomic phage phi29 DNA molecules with specific sizes was observed after prolonged infection times with delayed lysis phage mutants. Whereas the majority of the molecules had a size of 4 kb, additional DNA species were observed with sizes of 8.2, 6.5, 2.3, 2 and 1 kb. Most of the molecules were shown to originate from the right end of… CONTINUE READING