DNA polymerase III accessory proteins. V. Theta encoded by holE.

  title={DNA polymerase III accessory proteins. V. Theta encoded by holE.},
  author={Patricia S. Studwell-Vaughan and Mike O'Donnell},
  journal={The Journal of biological chemistry},
  volume={268 16},
The polIII core subassembly of DNA polymerase III holoenzyme is composed of the alpha (DNA polymerase), epsilon (editing exonuclease), and theta subunits. We have identified holE encoding theta (8.6 kDa) at 40.4 min, expressed and purified 300 mg of theta, and have studied its function by constituting the polIII core from pure alpha, epsilon, and theta subunits. The theta subunit binds the epsilon proofreader tightly, but it does not form a detectable complex with alpha. The epsilon subunit… CONTINUE READING

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 42 extracted citations

Similar Papers

Loading similar papers…