DNA ploidy in cell nuclei from paraffin-embedded material--comparison of results from two laboratories.

@article{Fossa1992DNAPI,
  title={DNA ploidy in cell nuclei from paraffin-embedded material--comparison of results from two laboratories.},
  author={Sophie D Fossa and Andreas Berner and H{\aa}kon Waehre and Thomas K. Heiden and M. E. H. Juul and Dies van den Ouden and Erik Olai Pettersen and Naining Wang and Bernhard Tribukait},
  journal={Cytometry},
  year={1992},
  volume={13 4},
  pages={
          395-403
        }
}
In 49 pairs of contiguous sections from paraffin-embedded prostatic cancer tissue, the DNA indices (DIs) were determined by flow cytometry (FCM) at 2 different laboratories. In 3 of 45 pairs of evaluable nuclear suspensions, DIs of 1.1 (DNA aneuploid) were found at Laboratory 1, whereas all 3 tumours were classified as DNA diploid at Laboratory 2. In the remaining 42 specimens, the correlation between the DIs was excellent, though the application of strictly defined DNA ploidy ranges led to… CONTINUE READING
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