DNA origami based visualization system for studying site-specific recombination events.

Abstract

Site-specific recombination involves reciprocal exchange between defined DNA sites. The reaction initiates from the formation of a recombinase-DNA synaptic complex, in which two recombination sites arrange in an appropriate configuration. However, there is incomplete information about how the topological state of the substrate influences the synapsis and… (More)
DOI: 10.1021/ja408656y

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