DNA microsatellite analysis using ion-pair reversed-phase high-performance liquid chromatography.

@article{Devaney2000DNAMA,
  title={DNA microsatellite analysis using ion-pair reversed-phase high-performance liquid chromatography.},
  author={Joseph M. Devaney and James E. Girard and Michael A. Marino},
  journal={Analytical chemistry},
  year={2000},
  volume={72 4},
  pages={858-64}
}
Genotyping based on short tandem repeat (STR) regions is used in human identification and parentage testing, gene mapping studies, cancer diagnostics, and diagnosis of hereditary diseases. Analysis of STR systems using slab gel electrophoresis requires lengthy and labor-intensive procedures. Therefore, alternative methods such as capillary electrophoresis or ion-pair reversed-phase high-performance liquid chromatography (IPRP HPLC) have been used to analyze DNA. IPRP HPLC offers an attractive… CONTINUE READING

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