DNA microarrays on a dendron-modified surface improve significantly the detection of single nucleotide variations in the p53 gene

@article{Oh2005DNAMO,
  title={DNA microarrays on a dendron-modified surface improve significantly the detection of single nucleotide variations in the p53 gene},
  author={Soon Jin Oh and Jimin Ju and B C Kim and Eunsil Ko and Bong Jin Hong and J L Park and Joon Won Park and Kwan Yong Choi},
  journal={Nucleic Acids Research},
  year={2005},
  volume={33},
  pages={e90 - e90}
}
Selectivity and sensitivity in the detection of single nucleotide polymorphisms (SNPs) are among most important attributes to determine the performance of DNA microarrays. We previously reported the generation of a novel mesospaced surface prepared by applying dendron molecules on the solid surface. DNA microarrays that were fabricated on the dendron-modified surface exhibited outstanding performance for the detection of single nucleotide variation in the synthetic oligonucleotide DNA. DNA… CONTINUE READING
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