DNA microarray and proteomic analyses of the RpoS regulon in Geobacter sulfurreducens.

@article{Nez2006DNAMA,
  title={DNA microarray and proteomic analyses of the RpoS regulon in Geobacter sulfurreducens.},
  author={Cinthia N{\'u}{\~n}ez and Abraham Esteve-N{\'u}{\~n}ez and Carol S. Giometti and Sandra L. Tollaksen and Tripti Khare and Winston Lin and Derek R. Lovley and Barbara A. Meth{\'e}},
  journal={Journal of bacteriology},
  year={2006},
  volume={188 8},
  pages={
          2792-800
        }
}
The regulon of the sigma factor RpoS was defined in Geobacter sulfurreducens by using a combination of DNA microarray expression profiles and proteomics. An rpoS mutant was examined under steady-state conditions with acetate as an electron donor and fumarate as an electron acceptor and with additional transcriptional profiling using Fe(III) as an electron acceptor. Expression analysis revealed that RpoS acts as both a positive and negative regulator. Many of the RpoS-dependent genes determined… CONTINUE READING

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