DNA methyltransferase inhibitors in cancer: From pharmacology to translational studies.

Abstract

DNA methylation is a mammalian epigenetic mark that participates to define where and when genes are expressed, both in normal cells and in the context of diseases. Like other epigenetic marks, it is reversible and can be modulated by chemical agents. Because it plays an important role in cancer by silencing certain genes, such as tumour suppressor genes, it… (More)
DOI: 10.1016/j.bcp.2016.12.004

Cite this paper

@article{Pechalrieu2017DNAMI, title={DNA methyltransferase inhibitors in cancer: From pharmacology to translational studies.}, author={Dany Pechalrieu and Chantal Eti{\'e}vant and Paola B Arimondo}, journal={Biochemical pharmacology}, year={2017}, volume={129}, pages={1-13} }