DNA methylation-specific multiplex assays for body fluid identification

@article{An2012DNAMM,
  title={DNA methylation-specific multiplex assays for body fluid identification},
  author={Ja Hyun An and Ajin Choi and Kyoung-Jin Shin and Woo Ick Yang and Hwan Young Lee},
  journal={International Journal of Legal Medicine},
  year={2012},
  volume={127},
  pages={35-43}
}
Recent advances in whole-genome epigenetic analysis indicate that chromosome segments called tissue-specific differentially methylated regions (tDMRs) show different DNA methylation profiles according to cell or tissue type. Therefore, body fluid-specific differential DNA methylation is a promising indicator for body fluid identification. However, DNA methylation patterns are susceptible to change in response to environmental factors and aging. Therefore, we investigated age-related methylation… CONTINUE READING

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