DNA methylation profiles in cancer diagnosis and therapeutics

  title={DNA methylation profiles in cancer diagnosis and therapeutics},
  author={Yunbao Pan and Guohong Liu and Fuling Zhou and Bojin Su and Yirong Li},
  journal={Clinical and Experimental Medicine},
Cancer initiation and proliferation is regulated by both epigenetic and genetic events with epigenetic modifications being increasingly identified as important targets for cancer research. DNA methylation catalyzed by DNA methyltransferases (DNMTs) is one of the essential epigenetic mechanisms that control cell proliferation, apoptosis, differentiation… CONTINUE READING