DNA methylation profiles distinguish different subtypes of gastroenteropancreatic neuroendocrine tumors.

@article{HowKit2015DNAMP,
  title={DNA methylation profiles distinguish different subtypes of gastroenteropancreatic neuroendocrine tumors.},
  author={Alexandre How-Kit and Emelyne Dejeux and Bertrand Dousset and Victor Renault and Marion Baudry and Beno{\^i}t Terris and J{\"o}rg Tost},
  journal={Epigenomics},
  year={2015},
  volume={7 8},
  pages={1245-58}
}
AIM Most studies have considered gastroenteropancreatic neuroendocrine tumors (GEP-NETs) as a homogenous group of samples or distinguish only gastrointestinal from pancreatic endocrine tumors. This article investigates if DNA methylation patterns could distinguish subtypes of GEP-NETs. MATERIALS & METHODS The DNA methylation level of 807 cancer-related genes was investigated in insulinomas, gastrinomas, non-functioning pancreatic endocrine tumors and small intestine endocrine tumors… CONTINUE READING
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