DNA methylation patterns and epigenetic memory.

  title={DNA methylation patterns and epigenetic memory.},
  author={A. Bird},
  journal={Genes & development},
  volume={16 1},
  • A. Bird
  • Published 2002
  • Biology, Medicine
  • Genes & development
  • The character of a cell is defined by its constituent proteins, which are the result of specific patterns of gene expression. Crucial determinants of gene expression patterns are DNA-binding transcription factors that choose genes for transcriptional activation or repression by recognizing the sequence of DNA bases in their promoter regions. Interaction of these factors with their cognate sequences triggers a chain of events, often involving changes in the structure of chromatin, that leads to… CONTINUE READING
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