DNA methylation of the RIZ1 tumor suppressor gene plays an important role in the tumorigenesis of cervical cancer

@inproceedings{Cheng2010DNAMO,
  title={DNA methylation of the RIZ1 tumor suppressor gene plays an important role in the tumorigenesis of cervical cancer},
  author={HY Cheng and Ying Gao and Ge Lou},
  booktitle={European journal of medical research},
  year={2010}
}
OBJECTIVE The retinoblastoma protein-interacting zinc finger gene RIZ1 is a tumor suppressor gene and a member of a nuclear histone/protein methyltransferase superfamily. The purpose of the present study was to examine the expression of RIZ1 and evaluate its carcinogenesis in cervical cancer. The relationship between DNA methylation and transcriptional silencing of RIZ1 was investigated in cervical cancer. METHODS RIZ1 expression was examined in cervical cancer cell lines and cervical tissues… CONTINUE READING
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