DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk

@inproceedings{Dayeh2016DNAMO,
  title={DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk},
  author={Tasnim Dayeh and Tiinamaija Tuomi and Peter Almgren and Alexander Perfilyev and Per-Anders Jansson and Vanessa D de Mello and Jussi Pihlajam{\"a}ki and Allan Vaag and Leif Groop and Emma Larsdotter Nilsson and Charlotte Ling},
  booktitle={Epigenetics},
  year={2016}
}
Identification of subjects with a high risk of developing type 2 diabetes (T2D) is fundamental for prevention of the disease. Consequently, it is essential to search for new biomarkers that can improve the prediction of T2D. The aim of this study was to examine whether 5 DNA methylation loci in blood DNA (ABCG1, PHOSPHO1, SOCS3, SREBF1, and TXNIP), recently reported to be associated with T2D, might predict future T2D in subjects from the Botnia prospective study. We also tested if these CpG… CONTINUE READING
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