DNA methylation landscapes: provocative insights from epigenomics

@article{Suzuki2008DNAML,
  title={DNA methylation landscapes: provocative insights from epigenomics},
  author={Miho Suzuki and Adrian Bird},
  journal={Nature Reviews Genetics},
  year={2008},
  volume={9},
  pages={465-476}
}
The genomes of many animals, plants and fungi are tagged by methylation of DNA cytosine. To understand the biological significance of this epigenetic mark it is essential to know where in the genome it is located. New techniques are making it easier to map DNA methylation patterns on a large scale and the results have already provided surprises. In particular, the conventional view that DNA methylation functions predominantly to irreversibly silence transcription is being challenged. Not only… CONTINUE READING
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