DNA methylation landscapes: provocative insights from epigenomics

@article{Suzuki2008DNAML,
  title={DNA methylation landscapes: provocative insights from epigenomics},
  author={M. Suzuki and A. Bird},
  journal={Nature Reviews Genetics},
  year={2008},
  volume={9},
  pages={465-476}
}
  • M. Suzuki, A. Bird
  • Published 2008
  • Medicine, Biology
  • Nature Reviews Genetics
  • The genomes of many animals, plants and fungi are tagged by methylation of DNA cytosine. To understand the biological significance of this epigenetic mark it is essential to know where in the genome it is located. New techniques are making it easier to map DNA methylation patterns on a large scale and the results have already provided surprises. In particular, the conventional view that DNA methylation functions predominantly to irreversibly silence transcription is being challenged. Not only… CONTINUE READING

    Figures, Tables, and Topics from this paper.

    Explore Further: Topics Discussed in This Paper

    Exposing the DNA methylome iceberg.
    • 96
    • PDF
    DNA methylation: superior or subordinate in the epigenetic hierarchy?
    • 350
    Function and information content of DNA methylation
    • 993
    DNA methylation systems and targets in plants
    • 59
    Phylogeny of Methylomes
    • 53

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 113 REFERENCES
    Epigenetic inheritance in plants
    • 654
    • PDF
    DNA methylation dynamics in plant genomes.
    • 156
    • PDF
    Genome-wide analysis of DNA methylation patterns
    • 267
    • PDF
    DNA methylation profiling of human chromosomes 6, 20 and 22
    • 1,253
    • PDF