DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus

Abstract

DNA methylation is of pivotal importance during development. Previous genome-wide studies identified numerous differentially methylated regions upon differentiation of stem cells, many of them associated with transcriptional start sites. We present the first genome-wide, single-base-resolution view into DNA methylation dynamics during differentiation of a… (More)
DOI: 10.1186/gb-2013-14-5-r50

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