DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific.

@article{Tobi2009DNAMD,
  title={DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific.},
  author={Elmar W. Tobi and L. H. Lumey and Rudolf P Talens and Dennis Kremer and Hein Putter and Aryeh D Stein and Pieternella E Slagboom and Bastiaan T Heijmans},
  journal={Human molecular genetics},
  year={2009},
  volume={18 21},
  pages={4046-53}
}
Prenatal famine in humans has been associated with various later-life consequences, depending on the gestational timing of the insult and the sex of the exposed individual. Epigenetic mechanisms have been proposed to underlie these associations. Indeed, animal studies and our early human data on the imprinted IGF2 locus indicated a link between prenatal nutritional and DNA methylation. However, it remains unclear how common changes in DNA methylation are and whether they are sex- and timing… CONTINUE READING
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