DNA methylation controls the responsiveness of hepatoma cells to leukemia inhibitory factor.

Abstract

The related members of the interleukin 6 (IL-6) family of cytokines, IL-6, leukemia inhibitory factor (LIF), and oncostatin M, act as major inflammatory mediators and induce the hepatic acute phase reaction. Normal parenchymal liver cells express the receptors for these cytokines, and these receptors activate, to a comparable level, the intracellular… (More)

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Cite this paper

@article{Blanchard2003DNAMC, title={DNA methylation controls the responsiveness of hepatoma cells to leukemia inhibitory factor.}, author={Fr{\'e}d{\'e}ric Blanchard and Erin Tracy and Joseph Smith and Souvik Chattopadhyay and Yanping Wang and W. Held and Heinz Baumann}, journal={Hepatology}, year={2003}, volume={38 6}, pages={1516-28} }