DNA methylation as a long-term biomarker of exposure to tobacco smoke.

Abstract

BACKGROUND Most biomarkers of exposure tend to have short half-lives. This includes cotinine, a metabolite of nicotine widely used to assess smoke exposure. Cotinine is thus unsuitable as a determinant of past exposure to cigarette smoke. METHODS We used bisulphite pyrosequencing of a set of four genomic loci (AHRR, 6p21, and two at 2q37) that had… (More)
DOI: 10.1097/EDE.0b013e31829d5cb3

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Cite this paper

@article{Shenker2013DNAMA, title={DNA methylation as a long-term biomarker of exposure to tobacco smoke.}, author={Natalie S. Shenker and Per Magne Ueland and Silvia Polidoro and Karin van Veldhoven and F Ricceri and Robert Brown and James M. Flanagan and Paolo Vineis}, journal={Epidemiology}, year={2013}, volume={24 5}, pages={712-6} }