DNA methylation and chromatin accessibility profiling of mouse and human fetal germ cells


Chromatin remodeling is important for the epigenetic reprogramming of human primordial germ cells. However, the comprehensive chromatin state has not yet been analyzed for human fetal germ cells (FGCs). Here we use nucleosome occupancy and methylation sequencing method to analyze both the genome-wide chromatin accessibility and DNA methylome at a series of… (More)
DOI: 10.1038/cr.2016.128


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